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Synthesis of new olefin chalcone derivatives as antitumor, antioxidant and antimicrobial agents

✍ Scribed by Babasaheb P. Bandgar, Shivkumar S. Jalde, Laxman K. Adsul, Sadanand N. Shringare, Shrikant V. Lonikar, Rajesh N. Gacche, Nagesh A. Dhole, Shivraj H. Nile, Amol L. Shirfule


Book ID
118778212
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
360 KB
Volume
21
Category
Article
ISSN
1054-2523

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Piperidine-mediated synthesis of thiazol
✍ P. Venkatesan; T. Maruthavanan πŸ“‚ Article πŸ“… 2011 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 107 KB

## Abstract A series of new thiazolyl chalcones, 1‐[2‐amino‐4‐methyl‐1, 3‐thiazol‐5‐yl]‐3‐aryl‐prop‐2‐en‐1‐one were prepared by piperidine mediated Claisen‐Schmidt condensation of thiazolyl ketone with substituted aromatic aldehyde. These chalcones on cyclization gave 2‐amino‐6‐(2‐amino‐4‐methyl‐1,