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Synthesis of new macrocyclic lactams, lactones, and thiolactones

✍ Scribed by A. A. Yavolovskii; É. I. Ivanov; Yu. É. Ivanov


Book ID
105106070
Publisher
Springer US
Year
1996
Tongue
English
Weight
267 KB
Volume
32
Category
Article
ISSN
0009-3122

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📜 SIMILAR VOLUMES


ChemInform Abstract: Synthesis of New Ma
✍ A. A. YAVOLOVSKII; E. I. IVANOV; YU. E. IVANOV 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

Synthesis of New Macrocyclic Lactames, Lactones, and Thiolactones. -A new and general method for the synthesis of macrocyclic lactones (II) , lactames (IV), and thiolactones (VI) using the tosyl chloride mediated cyclization of heteroaromatic amino acids is developed. -(YAVOLOVSKII,

Synthesis of macrocyclic lactams and lac
✍ William P.D. Goldring; AndréS. Hodder; Larry Weiler 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 254 KB

## A&Wrack Lactones and lactams 4-6 were synthesized from a series of acyclic dienes 1-3 via ringclosing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the UZratios compared to values from molecular mechanics calculations.