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Synthesis of New Glycerolipids Linked to Hydroxamate Derivatives Designed for Two-Dimensional Crystallization of Aminopeptidase M

✍ Scribed by Jean-Michel Altenburger; Luc Lebeau; Charles Mioskowski; Daniel Schirlin

Publisher: John Wiley and Sons
Year: 1992
Tongue: German
Weight: 466 KB
Volume: 75
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19920750808

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✦ Synopsis

Abstract

The synthesis of glycerolipids linked to hydroxamate derivatives designed for two‐dimensional crystallization of aminopeptidase M is reported. The lipid moieties are readily obtained using a convergent pathway. Their structure allows the introduction of a wide variety of ligands of biological interest.

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