An efficient three step process for the synthesis of chiral, nonracemic methyleneaziridines derived from homochiral [3-amino alcohols is described. Methyleneaziridines 4a-e produced using this chemistry have been shown to possess high enantiomeric purities (>\_ 95%ee).
✦ LIBER ✦
Synthesis of new chiral amino ether derivatives: synthetic application of meso aziridinium ions prepared from β-amino alcohols
✍ Scribed by Mariappan Periasamy; Muthu Seenivasaperumal; Vutukuri Dharma Rao
- Book ID
- 108283854
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 373 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0957-4166
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