Synthesis of new 7-membered α-phenylthio cyclic oxamides: HIV inhibitors

✍ Scribed by M. Medou; G. Priem; G. Quélever; M. Camplo; J.L. Kraus

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 200 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00680-7

✦ Synopsis

Based on the concept of bioisosterism, we report the computer design and the synthesis of original 7-membered ct-phenylthio cyclic oxamides with potent anti HIV-1 properties.