Synthesis of New 3-Phenoxypropan-2-ols with Various Heterocyclic Substituents.
โ Scribed by E. G. Mesropyan; G. B. Ambartsumyan; A. A. Avetisyan; A. S. Galstyan; I. R. Arutyunova
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 18 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
We have developed a method for the solid-phase synthesis of quinazoline-2,4-diones with various substituents on the aromatic ring. Although there have been numerous reports of the solid-phase synthesis of quinazoline-2,4-diones, they were not applicable to the synthesis of the quinazoline-2,4-diones
Indole-2,3-dione ivas treated with malonic acid in a mixture of-ethanol/p?v-idine to afford I - [3-(2-oxoindoliii?.lideiiej]acetic acid (31, ivhich was theta reacted with thionFl chloride to give the corresponding acid chloride (4). The acid chloride 4 reacted with arenes in the presence of AlC1, to