Synthesis of new 3-methylthio-5-aryl-4-isothiazolecarbonitriles with broad antiviral spectrum
✍ Scribed by C.C.C Cutrı̀; A Garozzo; M.A Siracusa; A Castro; G Tempera; M.C Sarvà; F Guerrera
- Book ID
- 114144431
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 190 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0166-3542
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## Abstract Novel substituted derivatives of 3‐aryl‐5‐cyano‐6‐methylthiopyrimidine‐2, 4‐diones were synthesized by the reaction of ethyl 2‐cyano‐3,3′‐dimethylthioacrylate with arylureas in good yields. The structures of all title compounds were evaluated by elemental analyses and ^1^H NMR spectra a