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Synthesis of new 3-(4-oxo-4H-chromen-3-yl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione derivatives by 1,3-dipolar cycloaddition reaction

✍ Scribed by Zhengfeng Xie; Fangming Liu; Yonghai Hui; Caihong Liu; Yadong Sun

Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
39 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis

A series of new 3-(4-oxo-4H-chromen-3-yl)-3a,6a-dihydropyrrolo [3,4-d]isoxazole-4,6-dione have been synthesized by the reaction of N-arylmaleimides with nitrile oxide, prepared from α-chloro-4-oxo-4Hchromen-carbaldehyde oximes in situ through 1,3-dipolar cycloaddition reaction. The structures of all new compounds were confirmed by elemental analysis, ir, 1 H nmr and mass spectral data.

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