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Synthesis of new 2,3-dihydrofuran-3-one derivative and its reactions with some primary amines

✍ Scribed by Ş. H. Üngören; M. Saçmaci; Y. Akçamur; C. Arici; D. Ülkü


Publisher
Journal of Heterocyclic Chemistry
Year
2004
Tongue
English
Weight
174 KB
Volume
41
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The Wittig reaction of 2,3‐dihydro‐4‐(4‐methoxybenzoyl)‐5‐(4‐methoxyphenyl)‐furan‐2,3‐dione (1) with methyl (triphenylphosphoranylidene)acetate (2) stereo‐ and regioselectively afforded methyl (Z)‐[2,3‐dihydro‐4‐(4‐methoxybenzoyl)‐5‐(4‐methoxyphenyl)‐3‐oxofuran‐2‐ylidene]acetate (3) in good yield. The reactions of 3 with primary amines (4a‐k) gave corresponding 1‐substituted 2,3‐dihydro‐1__H__pyrrol‐3‐ones (5a‐k).


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