Synthesis of new 2,3-dihydrofuran-3-one derivative and its reactions with some primary amines
✍ Scribed by Ş. H. Üngören; M. Saçmaci; Y. Akçamur; C. Arici; D. Ülkü
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2004
- Tongue
- English
- Weight
- 174 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
The Wittig reaction of 2,3‐dihydro‐4‐(4‐methoxybenzoyl)‐5‐(4‐methoxyphenyl)‐furan‐2,3‐dione (1) with methyl (triphenylphosphoranylidene)acetate (2) stereo‐ and regioselectively afforded methyl (Z)‐[2,3‐dihydro‐4‐(4‐methoxybenzoyl)‐5‐(4‐methoxyphenyl)‐3‐oxofuran‐2‐ylidene]acetate (3) in good yield. The reactions of 3 with primary amines (4a‐k) gave corresponding 1‐substituted 2,3‐dihydro‐1__H__pyrrol‐3‐ones (5a‐k).
📜 SIMILAR VOLUMES
Indole-2,3-dione ivas treated with malonic acid in a mixture of-ethanol/p?v-idine to afford I - [3-(2-oxoindoliii?.lideiiej]acetic acid (31, ivhich was theta reacted with thionFl chloride to give the corresponding acid chloride (4). The acid chloride 4 reacted with arenes in the presence of AlC1, to