Synthesis of New 2-(para-Aminobenzenesulfamido)-4,6- dimethylpyrimidine Derivatives
✍ Scribed by É. G. Mesropyan; G. B. Ambartsumyan; A. A. Avetisyan; M. G. Sargsyan
- Book ID
- 110291418
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 62 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0091-150X
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Synthesis of a series of new 4-substituted-3-aryl-1-(2,6-dimethylpyrimidin-4-yl)pyrazoles (2a-g, 3ag, and 4a-g) is described. All the synthesized compounds were evaluated in vitro for their antibacterial activity against two gram-positive and two gram-negative bacteria, namely, Bacillus subtilis (MT
## Abstract Mild and efficient synthesis of new synthetically useful aryliodonium ylides of 2,6‐dimethyl‐ pyrimidin‐4‐ol (**3a–d**) using (dichloroiodo)arenes in aqueous medium is reported. Antibacterial activity of these ylides **3a–d** against Escherichia coli and Bacillus Licheniformis is also d