## Abstract The reaction of dimethylpyrimidinol (I) with dichloroiodoarenes (II) in aqueous medium provides an easy access to aryliodonium ylides (III).
Mild and efficient synthesis of aryliodonium ylides of 2,6-dimethylpyrimidin-4-ol
β Scribed by Ravi Kumar; Reshmi R. Nair; Om Prakash
- Book ID
- 102233758
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 151 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1042-7163
- DOI
- 10.1002/hc.20608
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β¦ Synopsis
Abstract
Mild and efficient synthesis of new synthetically useful aryliodonium ylides of 2,6βdimethylβ pyrimidinβ4βol (3aβd) using (dichloroiodo)arenes in aqueous medium is reported. Antibacterial activity of these ylides 3aβd against Escherichia coli and Bacillus Licheniformis is also described. Β© 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:339β342, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20608
π SIMILAR VOLUMES
Synthesis of a series of new 4-substituted-3-aryl-1-(2,6-dimethylpyrimidin-4-yl)pyrazoles (2a-g, 3ag, and 4a-g) is described. All the synthesized compounds were evaluated in vitro for their antibacterial activity against two gram-positive and two gram-negative bacteria, namely, Bacillus subtilis (MT