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Synthesis of New 2-[1(2H)-Phthalazinon-2-yl]acetamide and 3-[1(2H)-Phthalazinon-2-yl]propanamide Derivatives as Antinociceptive and Anti-inflammatory Agents

โœ Scribed by Deniz S. Dogruer; Esra Kupeli; Erdem Yesilada; M. Fethi Sahin


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
98 KB
Volume
337
Category
Article
ISSN
0365-6233

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Synthesis and Antinociceptive Activity o
โœ Tijen ร–nkol; Engin Yildirim; Kevser Erol; Shigero Ito; M. Fethi ลžahin ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 92 KB ๐Ÿ‘ 2 views

## Abstract Ten new (5โ€chloroโ€2(3H)โ€benzothiazolonโ€3โ€yl)propanamide derivatives have been synthesized. The compounds were tested for antinociceptive activity by tail clip, tail flick, hot plate and writhing test by using aspirin and dipyrone as standards. Among these compounds, 1โ€[3โ€(5โ€chloroโ€2(3H)