Synthesis of new 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-ones under catalyst-free and solvent-free conditions
โ Scribed by Niknam, Khodabakhsh; Mojikhalifeh, Sanaz
- Book ID
- 121563327
- Publisher
- Springer
- Year
- 2013
- Tongue
- English
- Weight
- 231 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1381-1991
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๐ SIMILAR VOLUMES
## Abstract The catalyst can be recycled without significant loss in activity.
## Abstract magnified image A solventโ and catalystโfree oneโpot threeโcomponent condensation reaction approach was developed for the synthesis of a new class of 3โ(2โฒโbenzothiazolyl)โ2,3โdihydroquinazolinโ4(1__H__)โones in relatively good yields.
A Ziegler-Natta catalyst system (TiCl 4 -MgCl 2 /magnesium chloride-methanol adduct) was efficiently found to catalyze the three component Biginelli reaction of an aldehyde, โค-keto ester, and urea or thiourea under solvent free conditions to afford the corresponding 3,4-dihydropyrimidin-2-(1H)-ones