Synthesis of naphthyridinone derivatives as potential antimalarials
โ Scribed by F. Ivy Carroll; Bertold D. Berrang; C. Preston Linn
- Book ID
- 112126487
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1981
- Tongue
- English
- Weight
- 576 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A series of 8-aminoquinolines, analogous to primaquine and carrying a substituent in position two, have been synthesized by standard methods and tested for activity against Plas- modium berghei in mice. The results of preliminary biological tests are reported.
Hydroperoxide derivatives of [~-oxa-substituted polyunsaturated fatty acids were prepared by 15-1ipoxygenase catalysed oxidation and perketal derivatives of fatty acid hydroperoxides were synthesized. The perketals are more stable than their parent fatty acid hydroperoxides, but less active as antim