Synthesis of Na-Protected Peptide Acids by the N→C Chain Extension Employing O,N-bis-Trimethylsilyl-amino Acids Using the Mixed Anhydride Method.

Synthesis of N-protected peptides by the

Synthesis of N-protected peptides by the o-nitrophenylsulfenyl group using o-nitrophenylsulfenyl N-carboxy α-amino acid anhydrides

✍ Ryoichi Katakai; Masanao Oya 📂 Article 📅 1975 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 482 KB 👁 1 views

## Abstract __N__‐protected peptides, which are important intermediates as a carboxyl component in the fragment condensation method, have been prepared in high yields by the reaction of __o__‐nitrophenylsulfenyl (Nps) __N__‐carboxy α‐amino acid anhydrides with unprotected peptides and amino acids i