In order to study the influence of the length of the amino acid chain of N,N-phthaloyl-amino acid amides as analogues of the former anticonvulsant taltrimide on the seizure-antagonizing activity glycine, beta-alanine and gamma-aminobutyric acid (GABA) derivatives were synthesized. The corresponding
Synthesis of N-Phthaloyl Derivatives of Amino Acids
โ Scribed by S. I. Zav'yalov; O. V. Dorofeeva; E. E. Rumyantseva; L. B. Kulikova; G. I. Ezhova; N. E. Kravchenko; A. G. Zavozin
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 137 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
๐ SIMILAR VOLUMES
## Abstract The synthesis of __N__โ[__N__โ(2โchloroethyl)โ__N__โnitrosocarbamoyl]amino acids and their anilides, congeners of __N__โ(2โchloroethyl)โ__N__โnitrosoureas, as potential antineoplastic substances is reported. __N__โ[__N__โ(2โchloroethyl)โ__N__โnitrosocarbamoyl]amino acids are prepared by
## Abstract For Abstract see ChemInform Abstract in Full Text.
Mannich-type reactions are powerful methods for the efficient synthesis of b-amino carbonyl compounds that are valuable intermediates for the construction of natural products, b-peptides, and peptidomimetics. For the efficient steric steering of Mannich reactions a method was developed that consists