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Synthesis of N-Acylamino-ethoxyacetic Acid Derivatives.

✍ Scribed by Ervin Korošec; Darja Poljšak; Uroš Urleb

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
197 KB
Volume
325
Category
Article
ISSN
0365-6233

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✦ Synopsis

In the course of our investigation towards the design and synthesis of potential immunomodulators related to muramyldipeptide'), N-acylaminoethoxyacetic acid derivatives were needed as valuable key intermediates for the synthesis of some model compounds.

Such aliphatic amino acid compounds in which the carboxylic group and an acylated amino group are separated by three or four units are useful in treatment of convulsive disorders and also have anxiolytic and sedative properties2). They are also suitable as ingredients in phosphate-free washing and cleaning agents3'.

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