Synthesis of N-acetyl derivatives of 17?-(2-amino-oxazol-4-yl)-steroids and revised structure of N-acetylated 4- or 4,5-disubstituted 2-amino-oxazoles
✍ Scribed by Rapi, Gianfranco; Ginanneschi, Mauro; Chelli, Mario; Boicelli, Andrea
- Book ID
- 119951593
- Publisher
- Royal Society of Chemistry
- Year
- 1978
- Weight
- 532 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1472-7781
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📜 SIMILAR VOLUMES
## Abstract Acid chlorides and anhydrides react with 2‐amino‐4‐alkyloxazoles in the presence of aluminum chloride to produce 5‐acyl substituted 2‐amino‐4‐alkyloxazoles in modest yields. However, in the absence of the Lewis acid reaction occurs at the amino group to give the corresponding amides. Th
## Abstract magnified image A series of __N__‐(3‐amino‐3,4‐dihydro‐4‐oxopyrimidin‐2‐yl)‐4‐chloro‐2‐mercapto‐5‐methylbenzenesulfonamide derivatives **10‐17** have been synthesized as potential anti‐HIV agents. The __in vitro__ anti‐HIV‐1 activity of these compounds has been tested at the national C