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Synthesis of N-[4-(propyl)cyclohexyl]-amides with anti-inflammatory and analgesic activities

✍ Scribed by Amedeo Pau; Gianpiero Boatto; Battistina Asproni; Michele Palomba; Luciana Auzzas; Riccardo Cerri; Francesco Palagiano; Walter Filippelli; Giuseppe Falcone; Giulia Motola


Book ID
114018823
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
117 KB
Volume
55
Category
Article
ISSN
0014-827X

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Synthesis, Analgesic and Anti-Inflammato
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## Abstract A series of 4‐(2‐phenoxyphenyl)semicarbazones was synthesized and evaluated for their analgesic and anti‐inflammatory activities. Several compounds (e.Β g. **10h**, **10i**, and **11i**) were found to be more potent than the reference drug mefenamic acid in the formalin test. Based on th