Synthesis of N-(2-pyridyl)cyanoacetamides and 4-amino-2H-pyrido-[1,2-a]pyrimidin-2-ones from ethyl cyanoacetate and 2-aminopyridine
✍ Scribed by V. A. Dorokhov; S. V. Baranin; A. Dib; V. S. Bogdanov; I. P. Yakovlev; G. A. Stashina; V. M. Zhulin
- Book ID
- 112447612
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 557 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1573-9171
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## Abstract We report the condensation of substituted 2‐aminopyridines 5 with β‐ketocarboxylic esters in polyphosphoric acid. In this reaction were obtained together with the target compounds, 4__H__‐pyrido[1,2‐__a__]pyrirnidin‐4‐ones 6 also the pyridin‐2‐ones 7. All the compounds 7 were tested for
## Abstract The quasi‐one pot synthesis of new 2‐aminopyrido[1,2‐__a__][1,3,5]triazin‐4‐ones starting from 2‐amino‐pyridine and 2‐aminopicolines is herein described in order to obtain a library of cyclic guanidines.