## Abstract The well established M~1~ selective muscarinergic antagonist Pirenzepine 11‐[2‐(4‐methyl‐piperazin‐1‐yl)‐acetyl]‐5,11‐dihydro‐benzo[e]pyrido[3,2‐b][1,4]diazepin‐6‐one (1) exhibits an unusual behaviour __in vivo__, which cannot be explained with M~1~ antagonism exclusively. One of the as
Synthesis of N-(2-[18F]fluoroethyl)-N′-methylthiourea: a hydrogen peroxide scavenger
✍ Scribed by C. Gilissen; G. Bormans; T. de Groot; A. Verbruggen
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- French
- Weight
- 382 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2135
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## Abstract Substitution of a halo atom (chloro or bromo) in easily prepared __N__‐haloacetyl‐anilines with no‐carrier added (NCA) cyclotron‐produced [^18^F]fluoride ion (^18^F, __t__~1/2~= 109.8 min; __β__^+^=96.9%), followed by reduction with borane–tetrahydrofuran (BH~3~–THF), provides an altern