Synthesis of Methylene-Expanded 2‘,3‘-Dideoxyribonucleosides
✍ Scribed by Jung, Michael E.; Kiankarimi, Mehrak
- Book ID
- 120633008
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 454 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
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## Abstract The 2′‐deoxyisoguanosine (1) was synthesized by a two‐step procedure from 2′‐deoxyguanosine (5). Amination of silylated 2′‐deoxyguanosine yielded 2‐amino‐2′‐deoxyadenosine (6) which was subjected to selective deamination of the 2‐NH~2~ group resulting in compound 1. Also 2′,3′‐dideoxyis
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