๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of methyl-substituted trans-fused tetrahydropyrans via 6-endo cyclization

โœ Scribed by Yuji Mori; Hiroki Furuta; Toyohisa Takase; Shinjiro Mitsuoka; Hiroshi Furukawa

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
241 KB
Volume
40
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

A stereocontrolled synthesis of methyl-substituted trans-fused tetrahydropyrans having methyl groups adjacent to the ring oxygen is described. The strategy involves the coupling reaction of sulfonyl-stabilized oxiranyl anions with triflates and 6-endo cyclization of their products.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of trans-syn-trans fused bis-p
Synthesis of trans-syn-trans fused bis-pyrans via endo-selective cyclizations of cyclic sulfates
โœ Frank E. McDonald; Prahlad Vadapally ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 250 KB

Acid-catalyzed cyclization of hydroxy-cyclic sulfates occurs with endo-regioselectivity affording bispyran products from substrates in which the nucleophilic hydroxyl and electrophilic cyclic sulfate groups are 1,2-trans-substituted on a cyclic pyran template. This methodology is demonstrated in an

ChemInform Abstract: Synthesis of trans-
ChemInform Abstract: Synthesis of trans-syn-trans Fused Bis-Pyrans via endo-Selective Cyclizations of Cyclic Sulfates.
โœ Frank E. McDonald; Prahlad Vadapally ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 2 views

Synthesis of trans-syn-trans Fused Bis-Pyrans via endo-Selective Cyclizations of Cyclic Sulfates. -The first examples of pyran ring formation from hydroxy-cyclic sulfate cyclization are reported. Thus, acid-catalyzed endo-regioselective cyclization of compounds (II) afford the trans-syn-trans fused