Synthesis of methyl (−)-homogabaculinate and a carba analogue of 5-enolpyruvylshikimic acid
✍ Scribed by Malcolm M. Campbell; Malcolm Sainsbury; Philip A. Searle; Gareth M. Davies
- Book ID
- 108381533
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 214 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Construction of the ether-linked methyl 5aЈ-carba-β-lactoside (3) and N-acetyl-5aЈ-carba-β-lactosaminide (4) were carried out starting from the coupling products 15 and 16, readily obtained by coupling between 1,2-anhydro-4,6-Obenzylidene-5a-carba-D-mannopyranose ( 7) and the oxide anions generated
Synthesis of Methyl 5a'-Carba-βlactoside and N-Acetyl-5a'-carba-β-lactosaminides, and Related 5a'-Carbadisaccharides. -The title compounds, e.g. (X) and (XV), which are potential enzyme inhibitors, are prepared using consecutive epimerization reactions as the key steps.