Synthesis of methyl 5-acetamido-3,4,5-trideoxy-4-guanidinyl-d-glycero-d-galacto-2-nonulopyranosidonic acid (4-deoxy-4-guanidino-Neu5Acα2Me)
✍ Scribed by Silvana Ciccotosto; Mark von Itzstein
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 153 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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A crystalline tetrabutylammonium salt of 7-hydroxy-4-methylcoumarin was prepared and shown to contain two coumarin residues for each ammonium group. Condensation of this salt with the glycosyl chloride of methyl 5-acetamido-4,7,8,9tetra-~-acetyl-3,5-ddeoxy-~-D~~ycero-D-gu~acto-2-non~opyr~osona~ in d
The novel influenza virus neuraminidase inhibitor GGI 67 (5-acetylamino-4-guan~d~no-2,6-anhydro-3,4,5-tr~deoxy-D-g~ycero-~-galacto-non-2-eno~c acid) was labelled with "C for use in positron emission tomographic studies of drug deposition following intranasal or inhaled administration. ["C]GG167 was