Syntheses of the title glycosides are described. The critical O-glycosylations were carried out in the presence of boron trifluoride etherate with a high degree of alpha-selectivity.
Synthesis of methyl 3-O-(2-O-methyl-α-l-fucopyranosyl)-α-l-rhamnopyranoside, methyl 3-O-α-l-rhamnopyranosyl-α-d-glucopyranoside, and methyl 3-O-[3-O-(2-O-methyl-α-l-fucopyranosyl)-α-l-rhamnopyranosyl]-α-l-rhamnopyranoside: di- and tri-saccharide segments of a lipo-oligosaccharide (LOS-1) of Mycobacterium szulgai
✍ Scribed by Mukund K. Gurjar; Prathama S. Mainkar
- Book ID
- 107727281
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 489 KB
- Volume
- 239
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
The title branched-trisaccharide derivatives (9 and 13) have been synthesised from methyl 2,3-O-(2-nitrobenzylidene)-a-L-rhamnopyranoside (2) using the 2nitrobenzylidene residue as a temporary blocking-group. Condensation of 2 with methyl (2,3,4-tri-O-acetyl-a-D-glucopyranosyl bromide)uronate afford
In a previous papeti in this series, we described the synthesis of L-fucosyldisaccharides having sulfate groups at C-3 or C-4. Such r\_-fucosyl-oligosaccharides occur naturally as a part of the structure of fucoidan, a sulfated L-fucose polysaccharide, know to possess anticoagulant acticity 3,4 This