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Synthesis of methyl 2,6-dideoxy-4-thio-α-D-ribo-hexopyranoside, a new thio sugar found in calichemicins

✍ Scribed by Kai Van Laak; Hans-Dieter Scharf


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
131 KB
Volume
30
Category
Article
ISSN
0040-4039

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Synthesis of Methyl 2,6-Dideoxy-4-thio-α
✍ Claßen, Arnold ;Scharf, Hans-Dieter 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 549 KB

## Abstract The 4‐thio analog of 2,6‐dideoxy‐D‐__ribo__‐hexopyranose (D‐digitoxose) is part of the saccharide chain of the calicheamicins and esperamicins. A straightforward synthesis of the 4‐thiodigitoxoside 12 as its diacetate 13 starting from methyl α‐D‐galactopyranoside (1) is described. Prope