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Synthesis of mammalian dolichols from plant polyprenols

โœ Scribed by Tetsuo Takigawa; Koichi Ibata; Masao Mizuno

Book ID
103040190
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
727 KB
Volume
51
Category
Article
ISSN
0009-3084

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Synthesis of mammalian dolichols from pl
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S)-Dolichols can be prepared from polyprenols extracted from Ginkgo biloba leaves by asymmetric hydrogenation. The dolichols are obtained in high yield and >95% optical purity. The dihydropolyisoprenols which comprise the homologous family of (S)-dolichols are crucial metabolites in glycoprotein bi