Synthesis of malonyl-coenzyme A from acetyl-coenzyme A and oxalosuccinate in mitochondria
✍ Scribed by W.C. Hülsmann
- Book ID
- 118316806
- Publisher
- Elsevier Science
- Year
- 1963
- Weight
- 123 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0006-3002
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📜 SIMILAR VOLUMES
A method for the synthesis of [14C]malonyl-Coenzyme A starting with 10 mumol of [14C]malonate is reported. The synthesis is accomplished with yields of 48 +/- 4% (1 sigma, n = 6) using a procedure which does not require the isolation or purification of any intermediates.
The efficient microscale synthesis of \(\left[1-{ }^{14} \mathrm{C}\right]\) propionyl-CoA from commercially available sodium \(\left[1-{ }^{14} \mathrm{C}\right]-\) propionate using 1,1 'carbonyldiimidazole in yields of nearly \(\mathbf{7 0 \%}\) is reported for the first time. A substantial improv