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Synthesis of Lysine-vasopressin by the Nitrophenyl Ester Method 1

✍ Scribed by Bodanszky, Miklos; Meienhofer, Johannes; du Vigneaud, Vincent


Book ID
126177193
Publisher
American Chemical Society
Year
1960
Tongue
English
Weight
542 KB
Volume
82
Category
Article
ISSN
0002-7863

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The Synthesis of Lysine-vasopressin 1
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The hydrolysis of Ξ±-CBZ-l-lysine-p-nitro
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The catalytic properties of human urokinase have been investigated using a synthetic chromogenic substrate; a-CBZ-L-lysine-p-nitrophenyl ester (ZLNP). The enzymatic assay based on the rate of hydrolysis of ZLNP offers several advantages over other methods currently employed in different laboratories