๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of Long Chain Substituted 2-Imino-4-Thiazolidinones and 2, 4-Thiazolidinediones

โœ Scribed by Mukarram, M. ;Ahmad, I. ;Farooqi, Javed A. ;Ahmad, M.

Publisher
John Wiley and Sons
Year
1986
Weight
321 KB
Volume
88
Category
Article
ISSN
0931-5985

No coin nor oath required. For personal study only.

โœฆ Synopsis

The a-bromo palmitic, stearic and behenic acids on condensation with thiourea in the presence ofanhydrous sodium acetateyielded5-substituted- 2-imino-4-thiazolidinones in 80Yo.Acid hydrolysis of 5-substituted-2-imino-Cthiazolidinones afforded the 5-substituted-2,Cthiazolidinediones in 75 % yield. Structures of these compounds have been established with the help of combustion, IR, NMR and MS spectral studies.

๐Ÿ“œ SIMILAR VOLUMES

A novel synthesis of some 2-imino-4-thia
A novel synthesis of some 2-imino-4-thiazolidinone derivatives
โœ Firouz Matloubi Moghaddam; Leila Hojabri ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 386 KB

An efficient and simple route is presented to the synthesis of some iminothiazolidinone derivatives. ฮฑ-Chloro amide derivatives undergo coupling reaction with isothiocyanate in the presence of a mild base, followed by nucleophilic substitution of chlorine by the sulfur atom of isothiocyanate.