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Synthesis of lipoxin b

โœ Scribed by Joel Morris; Donn G. Wishka


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
266 KB
Volume
27
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Stereocontrolled Total Synthesis of Lipo
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Total synthesis of lipoxins A4 and B4 fr
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A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure a-hydroxy and a$-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material. Connection by a six carbons unit uses Wittig-type reactions notably involving a stabilized arsonium yl

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Data are presented which shows that the llpoxlns are formed via a tetraene epoxlde. supportlng the asslgnment of the all trans tetraene geometry to llpoxin B.