Synthesis of bifunctional cationic compo
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Tan Ren; Guisheng Zhang; Dexi Liu
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Article
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2001
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Elsevier Science
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French
โ 97 KB
Bifunctional cationic compound carrying trivalent galactosides as the cell targeting ligand and DAB-dendr-(NH 2 ) 8 (generation 2.0) as the DNA binding domain was synthesized for gene delivery to hepatocytes. DAB-dendr-(NH 2 ) 4 (generation 1.0) conjugated with a hydrocarbon chain was used as a scaf