Synthesis of lactosamine derivatives using β-d-galactosidase from Bacillus circulans
✍ Scribed by Shuichi Takayama; Makoto Shimazaki; Lei Qiao; Chi-Huey Wong
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 251 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
✦ Synopsis
Various lactosamine derivatives that are versatile building blocks for oligosaccharide synthesis were obtained with excellent regioselectivity and moderate to high yields using 13-D-galactosidase from Bacillus circulans as the biocatalyst.
📜 SIMILAR VOLUMES
Galβ1Ǟ4 disaccharide structures are vital core units of the rides {Galβ1Ǟ4GlcNAcαOAll (3), Galβ1Ǟ4GlcNAcβOAll (5), Galβ1Ǟ4GalαOAll (10), Galβ1Ǟ4GalβOAll (12), Galβ1Ǟ oligosaccharide components of glycoconjugates. β-Galactosidase from Bacillus circulans (E.C.3.2.1.23) catalyses the transfer 4GalβSPh
Different ethyl 1-thio-1]-D-disaccharides have been synthesised by transgalactosylation using the 1]-gaiactosidase from Bacillus circulans as biocatalyst. This [~-
## Abstract The enzymatic synthesis of N‐acetyl‐lactosamine (LacNAc) by the transgalactosylation of N‐acetyl‐D‐glucosamine (GlcNAc), catalyzed by the β‐galactosidase from Bacillus circulans (BcβGal), was studied in hydro‐organic media, starting from o‐nitrophenyl‐β‐D‐galactopyranoside (oNPG) as a g
The aim of this research is to develop a model to describe oligosaccharide synthesis and simultaneously lactose hydrolysis. Model A (engineering approach) and model B (biochemical approach) were used to describe the data obtained in batch experiments with -galactosidase from Bacillus circulans at v