A bst rnct in buffer(pH 4) for 35 minutes at 97°C. The synthesis was complete in approximately 1 hour with a radiochemical yield of 50% , a specific activity of 65 Ci/mmol and a radiochemical purity of >95%. A non radioactive standard of L-6-iododopa was synthesized by the iododemercuration of a mer
Synthesis of L-6-[123I]iodo-m-tyrosine a potential spect brain imaging agent
✍ Scribed by Michael J. Adam; Yolanda Zea Ponce; Joffre M. Berry
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 295 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
L‐6‐[^123^I]Iodo‐m‐tyrosine was synthesized by the direct iodination of L‐m‐tyrosine with [^123^I]‐NaI and Chloramine‐T. The product was purified by reverse phase HPLC to give the final product in 57% radiochemical yield with a radiochemical purity of greater than 97%.
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