Synthesis of isoniazid from 4-cyanopyridine
β Scribed by T. P. Sycheva; T. N. Pavlova; M. N. Shchukina
- Book ID
- 111651833
- Publisher
- Springer
- Year
- 1972
- Tongue
- English
- Weight
- 242 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0091-150X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We report herein the kinetic studies on hydrolysis of three cyanopyridines in highβtemperature water. 3βCyanopyridine, 4βcyanopyridine and 2βcyanopyridine underwent consecutive hydrolysis to the corresponding pyridinecarboxamides and picolinic acids. Further decarboxylation to pyridine
Catalytic transformation of 4-picoline into 4-cyanopyridine with nitric oxide (NO) over nickel oxide aluminium oxide catalyst has been examined using a fixed bed reactor in the temperature range 280-440 "C, under atmospheric pressure. A number of NiO catalysts on different supports were prepared and