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Synthesis of Isocoumarins and α-Pyrones via Tandem Stille Reaction/Heterocyclization

✍ Scribed by Cherry, Khalil; Parrain, Jean-Luc; Thibonnet, Jérôme; Duchêne, Alain; Abarbri, Mohamed


Book ID
118058711
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
292 KB
Volume
70
Category
Article
ISSN
0022-3263

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Synthesis of isocoumarins and α-pyrones
✍ Tuanli Yao; Richard C Larock 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 122 KB

A variety of 3-substituted 4-iodoisocoumarins and 6-substituted 5-iodo-2(2H)-pyranones are readily prepared in excellent yields under mild reaction conditions by the reaction of o-(1-alkynyl)benzoates and (Z)-2-alken-4-ynoates with ICl.