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Synthesis of indolizine-5,8-diones and [3.2.2]cyclazines

✍ Scribed by Benjamin R. Yerxa; Harold W. Moore

Book ID
104214762
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
220 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis

The thermally induced ring expansion of 4-(I-pyrrolyl)-4trimethylsiloxycyctobutenones to 5hydroxy-8-trimethylsiloxyindolirines and their subsequent oxidatbn to the rare indolizine-5,8-dbnes is described. When the rearrangement is carried out in the presence of DMAD the indoliiines are trapped in an 8+2 cycbaddition to give [3.2.2Jcyclazines. Described here is a versatile synthesis of indolizine-5,8-diones 6a-f and pyrrolo[2,1,5-

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Herbicidal indolizine-5,8-diones: photos
Herbicidal indolizine-5,8-diones: photosystem I redox mediators
✍ Dr Stephen C Smith; Eric D Clarke; Stuart M Ridley; David Bartlett; Daren T Gree πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 156 KB

## Abstract 6,7‐Disubstituted indolizine‐5,8‐diones showed activity as herbicides, giving rapid desiccation symptomology in whole‐plant tests and bleaching in leaf‐disc assays. In isolated chloroplasts, such compounds initiated rapid uptake of oxygen in Photosystem I. A redox mediator mode of actio