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Herbicidal indolizine-5,8-diones: photosystem I redox mediators

✍ Scribed by Dr Stephen C Smith; Eric D Clarke; Stuart M Ridley; David Bartlett; Daren T Greenhow; Harry Glithro; Agnes Y Klong; Glynn Mitchell; Graham W Mullier


Book ID
105359617
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
156 KB
Volume
61
Category
Article
ISSN
1526-498X

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✦ Synopsis


Abstract

6,7‐Disubstituted indolizine‐5,8‐diones showed activity as herbicides, giving rapid desiccation symptomology in whole‐plant tests and bleaching in leaf‐disc assays. In isolated chloroplasts, such compounds initiated rapid uptake of oxygen in Photosystem I. A redox mediator mode of action was further supported by electrochemical studies. Several compounds described had low photostability, high volatility, hydrolytic instability or reactivity with glutathione. The detrimental effects that these factors may have had on expression of herbicidal activity are discussed. Copyright © 2004 Society of Chemical Industry