Synthesis of indazole-N-oxides via the 1,7-electrocyclization of azomethine ylides
✍ Scribed by Miklós Nyerges; Andrea Virányi; Weimin Zhang; Paul W. Groundwater; Gábor Blaskó; László Tőke
- Book ID
- 108282748
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- French
- Weight
- 191 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0040-4020
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The first example of the 1,7-electrocyclisation of a non-stabilised azomethine ylide, e.g. 2, onto a nitro group, to give a 1,2,6-oxadiazepine intermediate, e.g. 4, is reported. Subsequent ring contraction results in the formation of the indazole-Noxides 5, 12, and 14.
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