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Synthesis of Benz[5,6]azepino[4,3-b]indoles by 1,7-Electrocyclization of Azomethine Ylides.

โœ Scribed by Miklos Nyerges; Aron Pinter; Andrea Viranyi; Istvan Bitter; Laszlo Toeke


Publisher
John Wiley and Sons
Year
2005
Weight
21 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract Cyclic ฮฒโ€amino esters **4**, obtained from lactams, were condensed with indoleโ€2โ€carbonyl chloride to afford the corresponding amides. Similarly, unusual conditions led to cyclisation at the 3โ€position of the indole moiety in the presence of __p__TSA and ethylene glycol to afford previo