✍ Scribed by Xuan Zhao; Da-Qing Shi
No coin nor oath required. For personal study only.
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A short and facile synthesis of imidazo[1,2‐c]quinazolin‐5(6__H__)‐ones and benzimidazo[1,2‐c]quinazolin‐6(5__H__)‐ones was accomplished in good yields via the novel reductive cyclization of 2‐(2‐nitrophenyl)imidazoles or 2‐(2‐nitrophenyl)benzoimidazoles with isocyanates promoted by low‐valent titanium reagent. J. Heterocyclic Chem., (2010).
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## Abstract magnified image An efficient, convenient, one‐pot synthesis of imidazo[1,2‐__c__]quinazoline‐5(6__H__)‐thione and imidazo[1,2‐__c__]quinazolin‐5(6__H__)‐one was accomplished in good yields via the novel reductive cyclization of 2‐(2‐nitrophenyl)‐1__H__‐imidazoles with isothiocyanates or