Synthesis of hydroisoindoles via intramolecular Diels-Alder reactions
β Scribed by Alain Guy; Yvonne Graillot
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 198 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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Regio-and stereo-controlled routes to functionalised hydroisoindoles have been developed by reaction of aminodienes with unsaturated anhydrides or acid chlorides and subsequent elaboration of the Diels Alder adducts. A recent publication' notes the limited use of the intramolecular Diels Alder (IMDA
The intramolecular tiiels-Alder reaction of several substituted cyclopentadienes to functionalized tricyclic products, suitable for transformation to polyquinane natural products, is described. We have embarked on what promises to be an extremely versatile strategy for the synthesis 'of natural prod