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Synthesis of Hybrids of D-Glucose and D-Galactose with Pyrrolidine-Based Iminosugars as Glycosidase Inhibitors

✍ Scribed by Venkata Ramana Doddi; Hari Prasad Kokatla; A. P. John Pal; Ranjan K. Basak; Yashwant D. Vankar

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
250 KB
Volume
2008
Category
Article
ISSN
1434-193X

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✦ Synopsis

Abstract

Sugar–iminosugar hybrid molecules made up of D‐glucose and D‐galactose with pyrrolidine‐based iminosugars, viz. 1,4‐dideoxy‐1,4‐imino‐L‐xylitol and 1,4‐dideoxy‐1,4‐imino‐L‐lyxitol, are synthesized from glycal epoxides and found to be moderate glycosidase inhibitors. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

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Synthesis of Pyrrolidine-Based Imino Sug
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