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Synthesis of holomycin and derivatives

โœ Scribed by Ellis, John E.; Fried, John H.; Harrison, Ian T.; Rapp, Erich; Ross, Carl H.


Book ID
120644328
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
424 KB
Volume
42
Category
Article
ISSN
0022-3263

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## Abstract Esculetin (1) and the novel compounds 5โ€chloroesculetin (5) and 5โ€bromoesculetin (6) were obtained from a lightโ€induced cyclization of __trans__โ€caffeic acid (3) catalyzed by [FeNa(edta)] and/or H~2~SO~4~, HCI, or HBr (__Scheme 1__). The experimental conditions for __trans__โ€__cis__โ€iso