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Transcriptional analysis and proteomics of the holomycin gene cluster in overproducer mutants of Streptomyces clavuligerus

✍ Scribed by V. Robles-Reglero; I. Santamarta; R. Álvarez-Álvarez; J.F. Martín; P. Liras

Book ID
118474097
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
880 KB
Volume
163
Category
Article
ISSN
0168-1656

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The cefD and cefE genes of Nocardia lactamdurans, which encode isopenicillin N epimerase and deacetoxycephalosporin C synthase respectively, have been located 0.63 kb upstream from the lysine-6-amino-transferase (lat) gene. cefD contains an open reading frame (ORF) of 1197 nucleotides (nt) encoding