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Synthesis of heterocyclic compounds VII. 6-amino-2,4-diaryl-3,5-dicyano-4H-pyrans

✍ Scribed by M. Quinteiro; C. Seoane; J.L. Soto


Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
121 KB
Volume
18
Category
Article
ISSN
0040-4039

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✦ Synopsis


Only few methods for 4H-pyran synthesis are known. In them, carbonyl compounds (Z-4). pyrylium salts (5-7) or y-pyrones (8.9) a're used as starting materials.


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Synthesis of 2,6-Diamino-3,5-dicyano-4-ethyl-4H-thiopyran and Its Recyclization into 6-Amino-3,5-dicyano-4-ethylpyridine-2(1H)-thione. -Three component condensation of propionaldehyde with malononitrile and cyanothioacetamide provides the title diaminothiopyran (IV) which recyclizes at reflux into