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Synthesis of heterocyclic analogs of α-methyldopa

✍ Scribed by Jefferson W. Tilley; Paul Levitan; Richard W. Kierstead


Book ID
112125586
Publisher
Journal of Heterocyclic Chemistry
Year
1979
Tongue
English
Weight
273 KB
Volume
16
Category
Article
ISSN
0022-152X

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The synthesis of 13C-enriched α-methyldo
✍ Matthew M. Ames; Neal Castagnoli Jr. 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 French ⚖ 393 KB

## Abstract Alpha‐methyldopa hydrochloride, specifically labelled with ^13^C in the benzylic position, was prepared for use in biotransformation studies. Carbonation of the lithio derivative of 3,4‐dibenzyloxybenzene with ^13^CO~2~ (64 atom percent) was followed by LiA1H~4~ reduction of the resulti