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Synthesis of 1,2,3,4-tetrahydroisoquinolines from α-methyldopa

✍ Scribed by Schneur Rachlin; Karin Worning; Jens Enemark


Publisher
Elsevier Science
Year
1968
Tongue
French
Weight
168 KB
Volume
9
Category
Article
ISSN
0040-4039

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Photochemical synthesis of 1,2,3,4-tetra
✍ Masaki Ikeda; Ken-ichi Hirao; Yohmei Okuno; Naganori Numao; Osamu Yonemitsu 📂 Article 📅 1977 🏛 Elsevier Science 🌐 French ⚖ 793 KB

When N-chloroacetyl-3-hydroxybenzylamine (37) in aqueous acetonitrile was irradiated, both ortho and para photocyclizations with reference to the OH group occurred to give 7-and 5 -hydroxy -3 -oxo -1,2,3,4tetrahydroisoquinolines ($2, 53). Similarly, 1 -methylisoquinoline derivatives (54, 55) were sy