๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of (+)-hernandulcin and (+)-epihernandulcin

โœ Scribed by Jung Hun Kim; Hyun Jin Lim; Seung Hoon Cheon

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
57 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

+)-Hernandulcin 1, an extremely sweet bisabolane-type sesquiterpene, and (+)-epihernandulcin 2 were synthesized in six steps from (-)-isopulegol with 15 and 11% overall yields, respectively.

๐Ÿ“œ SIMILAR VOLUMES

A facile synthesis of (6S,1โ€ฒS)-(+)-herna
A facile synthesis of (6S,1โ€ฒS)-(+)-hernandulcin and (6S,1โ€ฒR)-(+)-epihernandulcin
โœ Jung Hun Kim; Hyun Jin Lim; Seung Hoon Cheon ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 176 KB

A facile total synthesis of (รพ)-hernandulcin (1) was accomplished from (2)-isopulegol in 6 steps with 15% overall yield. Epoxidation of (2)-isopulegol with m-chloroperbenzoic acid followed by opening of the epoxide 3a with prenyl Grignard afforded the tertiary alcohol 4a with correct C-6 and C-1 0 s

Enantiospecific synthesis of (+)-hernand
Enantiospecific synthesis of (+)-hernandulcin
โœ Francesco G. Gatti ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 150 KB

pulegol in seven steps and in 25% overall yield.